Lafforgue PF, Chagnaud CJ, Daver LMH, Daumen-Legré VMS, Peragut JC, Kasbarian MJ, Volot F, Acquaviva PC (1994) Intervertebral disk vacuum phenomenon secondary to vertebral collapse: prevalence and significance. Maldague BE, Noel HM, Malghem JJ (1978) The intravertebral vacuum cleft: a sign of ischemic vertebral collapse. Malghem JJ, Maldague BE, Labaisse MA, Dooms G, Duprez T, Devogelaer JP, Vande Berg B (1993) Intravertebral vacuum cleft: changes in content after supine positioning. Theodorou DJ (2001) The intravertebral vacuum cleft sign. On the other hand, its secondary aims are to review the medical literature about this sign and to show the clinical and radiological evolution after a percutaneous vertebroplasty. The aims of this paper are, on one hand, to communicate the clinical case of a 73-year-old osteoporotic woman with traumatic vertebral fractures who developed this sign in her radiological survey. The broad diagnosis is made by antero-posterior X-ray, but computed tomography scan (CT scan) and magnetic resonance imaging (MRI) may help with the differential diagnosis. Post-traumatic ischemic necrosis could be its physiopathological mechanism, along with other pathologies like osteoporosis, corticosteroid therapy, diabetes, arteriosclerosis, alcoholism, multiple myeloma, bone metastasis and osteomyelitis. It is composed of 95% nitrogen and small amounts of oxygen and carbon dioxide. The intravertebral vacuum cleft sign (VCS) is an uncommon radiological sign, characterized by a radiolucent zone in the vertebral body.
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